In vivo pharmacokinetic study of antibody conjugates
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The National Institutes of Health (NIH), under the Department of Health and Human Services, has issued a Presolicitation / Notice of Intent to award a Firm-Fixed-Price Purchase Order to Jackson Laboratory. This award is for an in vivo pharmacokinetic study of antibody conjugates to characterize their pharmacokinetics in a model reflecting human physiology. Interested small businesses are invited to submit capability statements. Responses are due by June 12, 2026, 11:00 p.m. EDT.
Scope of Work
The primary objective is to characterize the pharmacokinetics of optimized antibody-lectin conjugates. This will involve:
- Administering optimized conjugates intravenously in transgenic FcRn mice.
- Measuring remaining serum concentrations of conjugates via ELISA to predict serum half-life.
Contract & Timeline
- Contract Type: Anticipated Firm-Fixed-Price Purchase Order.
- Set-Aside: Open to various small business categories, including 8(a), service-disabled veteran owned, HUBZone, small disadvantaged, veteran-owned, and women-owned businesses.
- Response Due: June 12, 2026, 11:00 p.m. EDT.
- Published Date: June 4, 2026.
- Place of Performance: Bethesda, MD, United States.
Submission & Evaluation
This is not a request for competitive quotes. However, interested small businesses that believe they can perform this requirement may submit a written capability statement. The Government will review these statements to determine whether to compete the award. An award is anticipated approximately ten days after the notice date, contingent on the Government's determination of capability.
Contact Information
- Primary Contact: David Shen
- Email: david.shen@nih.gov