Intent to Sole Source - Tapestri Single-Cell DNA + Protein Reagent kit v3 & Tapestri® Single-Cell DNA Cartridge Kit v3

Form / Attachment / Pricing Sheet

This document is a quotation from Mission Bio for specific reagents and kits. It outlines the products offered, pricing, and terms of sale.

• Quote Number: MB-05951
• Quote Name: NIH_Jinxia_Cart_CoreKit (MBN-7859249)
• Product: Tapestri Single-Cell DNA + Protein Reagent kit v3
• Description: Includes reagents for single-cell DNA-seq and protein analysis, barcoding bead kit, and access to a cloud analysis pipeline. Does not include cartridge kits or oligo-tagged antibodies.
• Quantity: 1.00
• Sales Price: USD 20,750
• Subtotal: USD 20,750
• Shipping and Handling: USD 630
• Grand Total: USD 21,380
• Expiration Date: 4/30/2026

This quotation provides specific pricing and product details for a reagent kit. Bidders can use this information to understand the cost and components of the offered solution. The expiration date is important for order fulfillment timelines. Purchase orders should be submitted to ordersupport@missionbio.com. The document also references Mission Bio's Terms and Conditions, which govern the sale.

Statement of Work (SOW)

The Center for Cellular Engineering (CCE) at NIH requires a standing order for Mission Bio Tapestri sequencing reagents and kits to support single-cell DNA and protein analysis for CAR-T cell manufacturing and clinical research.

• Procure multi-type single-cell DNA and protein sequencing kits and reagents from Mission Bio.
• The contractor will ship reagents and kits according to a scheduled delivery agreement.
• Minimum shelf life requirements: 3 months for general reagents, 6 months for library generation kits from the date of delivery.
• The standing order may include, but is not limited to, Tapestri Single-Cell DNA + Protein Reagent kits (Part# MB03-0084).
• Contractor shall supply technical support for all kits and reagents at no additional cost.

Approximately six months: May 28, 2026 - November 27, 2026.

• Overnight delivery, Monday through Thursday.
• Ship to: Center for Cellular Engineering (CCE), NIH/CC, 10 Center Drive, Bldg. 10/ Rm. 7N208, Bethesda, MD 20892-1288, Attention: Jinxia Ma.
• Contractor bears the cost of replacement for damaged, defective, incorrect, or incomplete shipments.

$21,380.00

• Vendor must provide a report documenting the safe transport of cryopreserved patient cells.
• Vendor must ensure temperature and other parameters are maintained during reagent and kit shipment.
• Contractor shall provide hard copies of proofs of each product delivered and a PDF.

Other / Unclassified

This document is a Sole Source Justification and Approval (JOFOC) for the purchase of reagent kits from Mission Bio for their Tapestri platform. The Center for Cellular Engineering (CCE) at the National Institutes of Health (NIH) Clinical Center requires these kits to support their research in single-cell gene and protein expression analysis, specifically for streamlining the workflow of CAR T cells manufacturing and clinical research. The Tapestri platform enables simultaneous measurement of genotype and immunophenotype at the single-cell level, which is crucial for understanding tumor phylogenies, stratifying patients, and developing cancer treatments.

This justification indicates a sole-source acquisition, meaning the government intends to procure these specific reagent kits from Mission Bio without full and open competition. The justification cites FAR 13.106-1(b)(1) and FAR 13.501(a)(1)(ii) & 2(i) as the statutory authorities. Mission Bio is identified as the only vendor providing compatible reagent kits for their Tapestri instrument, which the CCE already possesses. The estimated value of this acquisition is $21,380.00. The agency plans to post a notice of intent on SAM.gov for 15 days. Potential bidders should note that this is a justification for a sole-source purchase, and the government believes Mission Bio is the only source capable of meeting their needs due to the specialized nature of the Tapestri platform and its associated reagent kits.