OpenEye Software Annual Licenses
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The Health and Human Services (HHS), specifically the National Center for Advancing Translational Sciences (NCATS), is soliciting proposals for OpenEye Software Annual Licenses. This requirement supports ongoing translational science and drug discovery activities. This is a Total Small Business Set-Aside. Proposals are due June 5, 2026, at 2:30 PM ET.
Scope of Work
NCATS requires the OpenEye Non-Profit Package, including modules such as BROOD, EON, FILTER, OEChem TK, OEDocking, OMEGA, OMEGA DB, pKa Prospector, QUACPAC, ROCS, SITEHOPPER, SPRUCE, SZMAP, SZYBKI, and VIDA, plus FastROCS Annual Evaluation licenses. The software must:
- Provide reinstatement of the existing OpenEye software subscription.
- Support molecular modeling, virtual screening, and computational chemistry workflows.
- Enable comparison of chemical structures by shape, electrostatics, and related properties.
- Support conformer generation, molecular preparation, docking, visualization, and analysis.
- Facilitate structure-activity relationship analysis and compound prioritization.
- Maintain compatibility with existing NCATS workflows and internally developed tools.
- Ensure continuity of scientific operations with minimal disruption.
- Include vendor licensing, updates, and support.
Contract & Timeline
- Type: Combined Synopsis/Solicitation (RFQ) under Simplified Acquisition Procedures (FAR Part 13.5).
- Product Service Code (PSC): 7A21 (Business Application Off The Shelf Software).
- Period of Performance: One (1) year base period, from June 15, 2026, to June 14, 2027.
- Set-Aside: Total Small Business.
- NAICS: 541511 (Custom Computer Programming Services) with a size standard of $134 million.
- Published Date: May 29, 2026.
- Proposal Due: June 5, 2026, at 2:30 PM ET.
Evaluation & Submission
Award will be made on a Lowest Priced Technically Acceptable (LPTA) basis. Technical acceptability is determined by the offeror's ability to provide the specified products/services. Offerors must submit discounted open market prices electronically to Damian.Hurge@hhs.gov, referencing solicitation 75N98026Q00472. Required information includes DUNS, TIN, Company Name/Address/Website, Point of Contact, Proposal Expiration Date, team entities, and Company Type (validated via Beta SAM). Offerors must be registered and have a valid certification in Beta SAM.
Additional Notes
All communications regarding this solicitation must be directed to Damian Hurge at Damian.Hurge@HHS.gov. Payment will be made monthly in arrears, requiring submission and approval of invoices via the Invoice Processing Platform (IPP). Applicable FAR clauses and HHS FAR Class Deviations are incorporated by reference.